The science behind Advanced Amino Formula (or PerfectAmino by Advanced Bionutritionals) lies in understanding how essential amino acids (EAAs) function in the body and in the specific formulation that seeks to optimize these processes.
The Scientific Basis: Essential Amino Acids and Protein Synthesis
The human body requires 20 different amino acids to build and repair proteins. Of these, 9 are considered essential, meaning our body cannot produce them and must obtain them through diet or supplementation. Advanced Amino Formula focuses precisely on these 8 specific essential amino acids (Leucine, Valine, Isoleucine, Lysine, Phenylalanine, Threonine, Methionine, and Tryptophan), excluding Histidine, as it is considered semi-essential and often produced by the body in sufficient quantities.
The main function of these amino acids is to act as building blocks of proteins. This process is known as protein synthesis. For protein synthesis to occur efficiently and for the body to build and repair tissue (especially muscle), all essential amino acids must be available in adequate amounts and in the correct proportions. If a single essential amino acid is missing (the so-called "limiting amino acid"), protein synthesis can be impaired, even if the others are abundant.
Why is Advanced Amino Formula Optimized?
The scientific proposition behind Advanced Amino Formula is that the specific ratio of amino acids present in it has been studied to be the most effective for protein synthesis in the human body, minimizing waste.
Ideal Ratio for Absorption and Utilization: Unlike other protein sources (such as whey protein or meat), which must be digested and broken down into individual amino acids before being utilized, the amino acids in Advanced Amino Formula are already in their free form. This allows for nearly instantaneous and complete absorption. The specific ratio is believed to be optimized for direct utilization in human protein synthesis, with minimal generation of nitrogenous waste (which would burden the kidneys).
Focus on BCAAs and Other EAAs: The prominent presence of BCAAs (Leucine, Isoleucine, and Valine) is crucial. Leucine, in particular, is recognized as the primary "trigger" for muscle protein synthesis (a process known as the mTOR pathway). By combining it with other EAAs in the correct ratio, the product aims to maximize the body's ability to build and repair muscle.
Minimum Metabolic Waste: When we ingest complete proteins (from food or other supplements), only a percentage of the amino acids are effectively used for protein synthesis; the remainder is metabolized for energy or excreted, generating byproducts. The scientific claim of Advanced Amino Formula is that, due to its formulation of free amino acids and the ideal ratio, it results in minimal waste (less than 1% residual), with almost all of it being utilized for protein building and repair.
Enhanced Benefits: This efficient utilization of amino acids translates into the observed benefits:
Accelerated Muscle Recovery: Amino acids are rapidly delivered to muscles for repair.
Increased Muscle Mass: Optimized support for protein synthesis.
Reduced Fatigue: By providing the necessary building blocks, it helps maintain muscle function.
Immune Support: Amino acids are vital for cellular and immune function.
In short, the science behind Advanced Amino Formula is based on the efficient and optimized delivery of essential amino acids to the body, ensuring that the building blocks are readily available in the ideal proportions to maximize protein synthesis and tissue repair and construction processes.